Every GTA 6 character Rockstar has confirmed, and how they connect
Two leads, a smuggler, a paranoiac, a club owner, a music manager and a rap duo. Here is the map of who knows who.

Rockstar has named a small cast, and the interesting part is how tightly they interlock. Almost nobody here is a standalone.
The leads
Jason Duval grew up around grifters, served in the Army, and came back to work for drug runners in the Keys. Lucia Caminos is the first woman Rockstar has written as a fully voiced lead in a mainline Grand Theft Auto, introduced leaving custody.
Each carries a separate Criminal Profile, which Rockstar has said tracks how you operate rather than scoring you good or evil.

Jason's circle, in the Keys
Brian Heder is an old smuggler still working out of a boat yard, and the man letting Jason stay rent-free, which puts Jason in someone's debt before the story even opens. His wife Lori works the same operation. Cal Hampton rounds it out: a conspiracy hobbyist who listens to Coast Guard radio for fun and turns up at The Rusty Anchor.
The Vice City side
Boobie Ike turned a street reputation into property, a strip club and a recording studio. That studio connects him to Dre'Quan Priest, a dealer whose actual ambition was always music, who manages Real Dimez, the duo of Bae-Luxe and Roxy.
Raymond runs drug production that supplies Boobie's club, which is where the legitimate portfolio stops being legitimate. He opens the Extended Look by getting a phone call from Ernesto, warning him police are coming, having arranged for them to come.
And one more
Raul Bautista is described as a bank robber and appears on the cover art alongside Jason, Lucia and Boobie Ike. How he connects has not been shown.
Full section: all characters in the wiki.
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